Mane was shown a straight red card, for raising his foot in a challenge with the City goalkeeper Ederson, in the first half of Liverpool’s 5-0 defeat on Saturday.
The Senegalese forward’s boot caught Ederson in the face on the edge of City’s penalty area and the 25-year-old was dismissed by referee Jon Moss.
Only a claim of wrongful dismissal would see Mane’s ban completely withdrawn. But that is unlikely so the forward still faces at least one game out.
Ederson was taken off on a stretcher with facial injuries following the incident in the first half, but is likely to return within two weeks according to Pep Guardiola.
Liverpool have the option to claim the ban represents excessive punishment and intend to do so. A successful appeal would see Mane’s ban reduced by either one or two matches.