“I have been profoundly saddened by the massacre last Sunday in Nigeria, inside a church, where innocent people were killed,” the pontiff said at the end of his weekly public audience at the Vatican.
“And sadly this morning we have news of violence in the Central African Republic against Christian communities.
“I hope all forms of hate and violence will cease and such shameful crimes in places of worship, where the faithful are gathered to pray, will not be repeated,” he added.
At least 11 worshippers were gunned down at a church in southeast Nigeria on Sunday, with authorities suggesting the bloodshed was due to a local feud.
Attacks on churches are rare in southern Nigeria, where there is a predominantly Christian population.
The country’s mainly-Muslim north has been gripped by a violent campaign by Boko Haram jihadists, who specialise in targeting religious centres.
The violent campaign to impose strict Islamic law has killed at least 20,000 people and forced some 2.6 million others to flee their homes, sparking a dire humanitarian crisis in the northeast.
In the Central African Republic, reports of killings, some targeting aid workers have prompted the UN to warn of “early signs of a genocide” in the conflict-wracked nation.
At least 60 people have been killed in recent weeks in fighting between armed groups in Ngaoundaye and Batangafo in the north, Kaga-Bandoro in the centre and Alindao and Gambo to the south, witnesses have told AFP.
The fighting is largely between groups on opposing sides of the brutal conflict between Muslim and Christian militias that broke out in CAR in 2013 after President Francois Bozize was overthrown by a coalition of Muslim-majority rebel groups called the Seleka.